I pass through there often on my way up to the Sierra and Yosemite. It's at low elevation there in California's Central Valley. Hot this time of year; plan on highs in the 90's, triple digits in summer. The "Cowboy Capitol of the World".
Have never fished the river. Check the regs for the section you plan to try; I think some sections like just downstream of Godwin dam is only open in winter on specific days of the week. From there it passes through a rocky gorge which is hard to access.
Downstream is a recreation area that is probably good for warm water fishing, but I'm not sure what kind of scene that is .... The part near town looks hard to bank fish (dense trees / brush); have seen pics of people kayak fishing it. Not sure if flows are too high right now, though. Dreamflows should tell you, and there are probably raft / kayak rental places that might know.
This time of year I'd head up 108 past Sonora into the Stanislaus NF instead, but that's just me. Yosemite is on a reservation system this year, so that might be tough.
Enjoy, and post pics